DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs

Genome-wide association studies have identified more than 100 SNPs that increase the risk of prostate cancer (PrCa). We identify and compare expression quantitative trait loci (eQTLs) and CpG methylation quantitative trait loci (meQTLs) among 147 established PrCa risk SNPs in primary prostate tumors...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Dai, James Y., Wang, Xiaoyu, Wang, Bo, Sun, Wei, Jordahl, Kristina M., Kolb, Suzanne, Nyame, Yaw A., Wright, Jonathan L., Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145271/
https://ncbi.nlm.nih.gov/pubmed/32226005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008667
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