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Inhibition of cytoplasmic cap methylation identifies 5′ TOP mRNAs as recapping targets and reveals recapping sites downstream of native 5′ ends

Cap homeostasis is the cyclical process of decapping and recapping that maintains the translation and stability of a subset of the transcriptome. Previous work showed levels of some recapping targets decline following transient expression of an inactive form of RNMT (ΔN-RNMT), likely due to degradat...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: del Valle Morales, Daniel, Trotman, Jackson B, Bundschuh, Ralf, Schoenberg, Daniel R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144985/
https://ncbi.nlm.nih.gov/pubmed/31996904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa046
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