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Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability

The notion that decapping leads irreversibly to mRNA decay changed with the identification of capped transcripts missing portions of their 5′ ends and a cytoplasmic complex that can restore the cap on uncapped mRNAs. The current study used accumulation of uncapped transcripts in cells inhibited for...

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Detalhes bibliográficos
Main Authors: Mukherjee, Chandrama, Patil, Deepak P., Kennedy, Brian A., Bakthavachalu, Baskar, Bundschuh, Ralf, Schoenberg, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462258/
https://ncbi.nlm.nih.gov/pubmed/22921400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.07.011
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