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A Zipf-plot based normalization method for high-throughput RNA-seq data
Normalization is crucial in RNA-seq data analyses. Due to the existence of excessive zeros and a large number of small measures, it is challenging to find reliable linear rescaling normalization parameters. We propose a Zipf plot based normalization method (ZN) assuming that all gene profiles have s...
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| Veröffentlicht in: | PLoS One |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144957/ https://ncbi.nlm.nih.gov/pubmed/32271772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230594 |
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