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Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data

BACKGROUND: Recently, rapid improvements in technology and decrease in sequencing costs have made RNA-Seq a widely used technique to quantify gene expression levels. Various normalization approaches have been proposed, owing to the importance of normalization in the analysis of RNA-Seq data. A compa...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Li, Peipei, Piao, Yongjun, Shon, Ho Sun, Ryu, Keun Ho
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625728/
https://ncbi.nlm.nih.gov/pubmed/26511205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0778-7
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