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A scaling normalization method for differential expression analysis of RNA-seq data
The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady state RNA. In order to discover biologically important changes in expression, we show that normalization continues to be an essential step in t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864565/ https://ncbi.nlm.nih.gov/pubmed/20196867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r25 |
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