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A scaling normalization method for differential expression analysis of RNA-seq data
The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady state RNA. In order to discover biologically important changes in expression, we show that normalization continues to be an essential step in t...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864565/ https://ncbi.nlm.nih.gov/pubmed/20196867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r25 |
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