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A Hypothesis Testing Based Method for Normalization and Differential Expression Analysis of RNA-Seq Data

Next-generation sequencing technologies have made RNA sequencing (RNA-seq) a popular choice for measuring gene expression level. To reduce the noise of gene expression measures and compare them between several conditions or samples, normalization is an essential step to adjust for varying sample seq...

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Vydáno v:PLoS One
Hlavní autoři: Zhou, Yan, Wang, Guochang, Zhang, Jun, Li, Han
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224994/
https://ncbi.nlm.nih.gov/pubmed/28072846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169594
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