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A Hypothesis Testing Based Method for Normalization and Differential Expression Analysis of RNA-Seq Data
Next-generation sequencing technologies have made RNA sequencing (RNA-seq) a popular choice for measuring gene expression level. To reduce the noise of gene expression measures and compare them between several conditions or samples, normalization is an essential step to adjust for varying sample seq...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224994/ https://ncbi.nlm.nih.gov/pubmed/28072846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169594 |
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