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Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

DNA methyltransferases are primary enzymes for cytosine methylation at CpG sites of epigenetic gene regulation in mammals. De novo methyltransferases DNMT3A and DNMT3B create DNA methylation patterns during development, but how they differentially implement genomic DNA methylation patterns is poorly...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lin, Chien-Chu, Chen, Yi-Ping, Yang, Wei-Zen, Shen, James C K, Yuan, Hanna S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144912/
https://ncbi.nlm.nih.gov/pubmed/32083663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa111
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