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Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic Candida Species

Opportunistic pathogens of the genus Candida reign as the leading cause of mycotic disease and are associated with mortality rates greater than 40%, even with antifungal intervention. This is in part due to the limited arsenal of antifungals available to treat systemic fungal infections. Azoles have...

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Bibliografiske detaljer
Udgivet i:mSphere
Main Authors: Revie, Nicole M., Robbins, Nicole, Whitesell, Luke, Frost, John R., Appavoo, Solomon D., Yudin, Andrei K., Cowen, Leah E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142304/
https://ncbi.nlm.nih.gov/pubmed/32269162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00256-20
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