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Oxadiazole-Containing Macrocyclic Peptides Potentiate Azole Activity against Pathogenic Candida Species

Opportunistic pathogens of the genus Candida reign as the leading cause of mycotic disease and are associated with mortality rates greater than 40%, even with antifungal intervention. This is in part due to the limited arsenal of antifungals available to treat systemic fungal infections. Azoles have...

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Publicado en:mSphere
Main Authors: Revie, Nicole M., Robbins, Nicole, Whitesell, Luke, Frost, John R., Appavoo, Solomon D., Yudin, Andrei K., Cowen, Leah E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142304/
https://ncbi.nlm.nih.gov/pubmed/32269162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00256-20
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