Transgenic Rescue of Spermatogenesis in Males With Mgat1 Deleted in Germ Cells

MGAT1 and complex N-glycans are required for spermatogenesis and fertility. Conditional deletion of Mgat1 in spermatogonia (Mgat1 cKO) causes reduced ERK1/2 signaling and the formation of multinucleated germ cells (MNC). Here we show that glycomics analysis of N-glycans released from fixed testis se...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Biswas, Barnali, Batista, Frank, Akintayo, Ayodele, Aguilan, Jennifer, Stanley, Pamela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142241/
https://ncbi.nlm.nih.gov/pubmed/32300591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00212
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