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PTGES/PGE(2) signaling links immunosuppression and lung metastasis in Gprc5a-knockout mouse model
Chronic inflammation has been linked to promotion of tumorigenesis and metastasis in lung. However, due to lack of a relevant animal model for characterization, the underlying mechanism remains elusive. Lung tumor suppressor gene Gprc5a-knockout (ko) mice are susceptible to lung inflammation, tumori...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7142021/ https://ncbi.nlm.nih.gov/pubmed/32060421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1207-6 |
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