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Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels
Pancreatic ductal adenocarcinoma (PDAC) responds poorly to checkpoint blockade, such as anti-CTLA-4 and anti-PD-1. Galectin-9, a β-galactoside-binding lectin, promotes immune suppression through T-cell inhibition, and programming of tolerogenic macrophages. Of all cancers tested, PDAC showed the hig...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7142017/ https://ncbi.nlm.nih.gov/pubmed/32055023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1186-7 |
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