Gamma-delta T cells stimulate IL-6 production by pancreatic stellate cells in pancreatic ductal adenocarcinoma

INTRODUCTION: The immunosuppressive tumor microenvironment promotes progression of pancreatic ductal adenocarcinoma (PDAC). γδ T cells infiltrate the pancreatic tumor stroma and support tumorigenesis through αβ T cell inhibition. Pancreatic stellate cell (PSC) activation contributes to pancreatic fi...

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Dettagli Bibliografici
Pubblicato in:J Cancer Res Clin Oncol
Autori principali: Seifert, Adrian M., List, Julian, Heiduk, Max, Decker, Rahel, von Renesse, Janusz, Meinecke, Ann-Christin, Aust, Daniela E., Welsch, Thilo, Weitz, Jürgen, Seifert, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Original Article – Cancer Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679341/
https://ncbi.nlm.nih.gov/pubmed/32865617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-020-03367-8
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