Detection of pancreatic ductal adenocarcinoma with galectin-9 serum levels

Pancreatic ductal adenocarcinoma (PDAC) responds poorly to checkpoint blockade, such as anti-CTLA-4 and anti-PD-1. Galectin-9, a β-galactoside-binding lectin, promotes immune suppression through T-cell inhibition, and programming of tolerogenic macrophages. Of all cancers tested, PDAC showed the hig...

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Udgivet i:Oncogene
Main Authors: Seifert, Adrian M., Reiche, Charlotte, Heiduk, Max, Tannert, Anna, Meinecke, Ann-Christin, Baier, Stephanie, von Renesse, Janusz, Kahlert, Christoph, Distler, Marius, Welsch, Thilo, Reissfelder, Christoph, Aust, Daniela E., Miller, George, Weitz, Jürgen, Seifert, Lena
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142017/
https://ncbi.nlm.nih.gov/pubmed/32055023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1186-7
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