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The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I
During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation. However, during female meiosis I, the resolution of chiasmata requires the proteolytic cleavage of cohesin subunit Rec8 along chromosome arms by Separase to separate homologs, a...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141834/ https://ncbi.nlm.nih.gov/pubmed/32284991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3969 |
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