Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis

Sister chromatid cohesion, mediated by cohesin complex and established by the acetyltransferases Esco1 and Esco2, is essential for faithful chromosome segregation. Mutations in Esco2 cause Roberts syndrome, a developmental disease characterized by severe prenatal retardation as well as limb and faci...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Lu, Yajuan, Dai, Xiaoxin, Zhang, Mianqun, Miao, Yilong, Zhou, Changyin, Cui, Zhaokang, Xiong, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766191/
https://ncbi.nlm.nih.gov/pubmed/28934466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx563
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