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The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I

During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation. However, during female meiosis I, the resolution of chiasmata requires the proteolytic cleavage of cohesin subunit Rec8 along chromosome arms by Separase to separate homologs, a...

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Vydáno v:Sci Adv
Hlavní autoři: Zhou, Changyin, Miao, Yilong, Cui, Zhaokang, ShiYang, Xiayan, Zhang, Yu, Xiong, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141834/
https://ncbi.nlm.nih.gov/pubmed/32284991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3969
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