BCG vaccination reduces the mortality of Mycobacterium tuberculosis–infected type 2 diabetes mellitus mice

Diabetes is a significant risk factor for the development of active tuberculosis. In this study, we used a mouse model of type 2 diabetes mellitus (T2DM) to determine the effect of prior Bacillus Calmette-Guérin (BCG) vaccination on immune responses to Mycobacterium tuberculosis (Mtb) infection. We...

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Pubblicato in:JCI Insight
Autori principali: Radhakrishnan, Rajesh Kumar, Thandi, Ramya Sivangala, Tripathi, Deepak, Paidipally, Padmaja, McAllister, Madeline Kay, Mulik, Sachin, Samten, Buka, Vankayalapati, Ramakrishna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141407/
https://ncbi.nlm.nih.gov/pubmed/32161191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133788
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