Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosis

In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during Mycobacterium tuberculosis (Mtb) infection. Alcohol increased the mortality of young mice but not old mice with Mtb infection. CD11b+Ly6G+ cells are...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Tripathi, Deepak, Welch, Elwyn, Cheekatla, Satyanarayana Swamy, Radhakrishnan, Rajesh Kumar, Venkatasubramanian, Sambasivan, Paidipally, Padmaja, Van, Abhinav, Samten, Buka, Devalraju, Kamakshi P., Neela, Venkata Sanjeev Kumar, Valluri, Vijaya Lakshmi, Mason, Carol, Nelson, Steve, Vankayalapati, Ramakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072099/
https://ncbi.nlm.nih.gov/pubmed/30071107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007174
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