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CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive neuromuscular disorder most commonly caused by mutations disrupting the reading frame of the dystrophin (DMD) gene. DMD codes for dystrophin, which is critical for maintaining the integrity of muscle cell membranes. Without dystrophin,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes (Basel)
Main Authors: Lim, Kenji Rowel Q., Nguyen, Quynh, Dzierlega, Kasia, Huang, Yiqing, Yokota, Toshifumi
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141101/
https://ncbi.nlm.nih.gov/pubmed/32213923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11030342
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