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CRISPR-Generated Animal Models of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive neuromuscular disorder most commonly caused by mutations disrupting the reading frame of the dystrophin (DMD) gene. DMD codes for dystrophin, which is critical for maintaining the integrity of muscle cell membranes. Without dystrophin,...

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Detalles Bibliográficos
Publicado en:Genes (Basel)
Main Authors: Lim, Kenji Rowel Q., Nguyen, Quynh, Dzierlega, Kasia, Huang, Yiqing, Yokota, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141101/
https://ncbi.nlm.nih.gov/pubmed/32213923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11030342
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