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Inherited DNA Repair Gene Mutations in Men with Lethal Prostate Cancer

Germline variants in DNA repair genes are associated with aggressive prostate cancer (PrCa). The aim of this study was to characterize germline variants in DNA repair genes associated with lethal PrCa in Finnish and Swedish populations. Whole-exome sequencing was performed for 122 lethal and 60 unse...

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Bibliografische gegevens
Gepubliceerd in:Genes (Basel)
Hoofdauteurs: Rantapero, Tommi, Wahlfors, Tiina, Kähler, Anna, Hultman, Christina, Lindberg, Johan, Tammela, Teuvo L. J., Nykter, Matti, Schleutker, Johanna, Wiklund, Fredrik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140841/
https://ncbi.nlm.nih.gov/pubmed/32183364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11030314
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