Inherited DNA Repair Gene Mutations in Men with Lethal Prostate Cancer

Germline variants in DNA repair genes are associated with aggressive prostate cancer (PrCa). The aim of this study was to characterize germline variants in DNA repair genes associated with lethal PrCa in Finnish and Swedish populations. Whole-exome sequencing was performed for 122 lethal and 60 unse...

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Hoofdauteurs: Tommi Rantapero, Tiina Wahlfors, Anna Kähler, Christina Hultman, Johan Lindberg, Teuvo L. J. Tammela, Matti Nykter, Johanna Schleutker, Fredrik Wiklund
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2020-03-01
Reeks:Genes
Onderwerpen:
prostate cancer
dna repair genes
lethal cancer
Online toegang:https://www.mdpi.com/2073-4425/11/3/314
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