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Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies

The human 80S ribosome is the cellular nucleoprotein nanomachine in charge of protein synthesis that is profoundly affected during cancer transformation by oncogenic proteins and provides cancerous proliferating cells with proteins and therefore biomass. Indeed, cancer is associated with an increase...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Gilles, Arnaud, Frechin, Léo, Natchiar, Kundhavai, Biondani, Giulia, von Loeffelholz, Ottilie, Holvec, Samuel, Malaval, Julie-Lisa, Winum, Jean-Yves, Klaholz, Bruno P., Peyron, Jean-François
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140421/
https://ncbi.nlm.nih.gov/pubmed/32151059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030629
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