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Structure–function insights reveal the human ribosome as a cancer target for antibiotics
Many antibiotics in clinical use target the bacterial ribosome by interfering with the protein synthesis machinery. However, targeting the human ribosome in the case of protein synthesis deregulations such as in highly proliferating cancer cells has not been investigated at the molecular level up to...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5052680/ https://ncbi.nlm.nih.gov/pubmed/27665925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12856 |
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