Loss of ISWI ATPase SMARCA5 (SNF2H) in Acute Myeloid Leukemia Cells Inhibits Proliferation and Chromatid Cohesion

ISWI chromatin remodeling ATPase SMARCA5 (SNF2H) is a well-known factor for its role in regulation of DNA access via nucleosome sliding and assembly. SMARCA5 transcriptionally inhibits the myeloid master regulator PU.1. Upregulation of SMARCA5 was previously observed in CD34+ hematopoietic progenito...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Zikmund, Tomas, Paszekova, Helena, Kokavec, Juraj, Kerbs, Paul, Thakur, Shefali, Turkova, Tereza, Tauchmanova, Petra, Greif, Philipp A., Stopka, Tomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139293/
https://ncbi.nlm.nih.gov/pubmed/32197313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21062073
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