Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5

CCCTC-binding factor (CTCF) can both activate as well as inhibit transcription by forming chromatin loops between regulatory regions and promoters. In this regard, Ctcf binding on non-methylated DNA and its interaction with the Cohesin complex results in differential regulation of the H19/Igf2 locus...

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Bibliografske podrobnosti
Main Authors: Dluhosova, Martina, Curik, Nikola, Vargova, Jarmila, Jonasova, Anna, Zikmund, Tomas, Stopka, Tomas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911986/
https://ncbi.nlm.nih.gov/pubmed/24498324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087448
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