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Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Infection caused by SARS-CoV-2 can result in severe respiratory complications and death. Patients with a compromised immune system are expected to be more susceptible to a severe disease course. In this report we suggest that patients with systemic lupus erythematous might be especially prone to sev...

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Pubblicato in:Clin Immunol
Autori principali: Sawalha, Amr H., Zhao, Ming, Coit, Patrick, Lu, Qianjin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139239/
https://ncbi.nlm.nih.gov/pubmed/32276140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2020.108410
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