Identification of somatic copy number variations in plasma cell free DNA correlating with intrinsic resistances to EGFR targeted therapy in T790M negative non-small cell lung cancer

BACKGROUND: About 20–30% EGFR-mutant non-small lung cancer show intrinsic resistance to EGFR targeted therapies. Compared to T790M positive in acquired resistance patients, little is known about EGFR-TKI intrinsic resistance for T790M negative patients. METHODS: Thirty-one patients with advanced sta...

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Bibliografiska uppgifter
I publikationen:J Thorac Dis
Huvudupphovsmän: Zhu, Lucheng, Liang, Jiafeng, Xia, Bing, Xu, Yasi, Qian, Ziliang, Ma, Shenglin, Zhang, Shirong
Materialtyp: Artigo
Språk:Inglês
Publicerad: AME Publishing Company 2020
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138977/
https://ncbi.nlm.nih.gov/pubmed/32274156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.12.97
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