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Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma

Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system. With no effective therapy, the prognosis for patients is terrible poor. It is highly heterogeneous and EGFR amplification is its most frequent molecular alteration. In this light, we aimed to examine the gen...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Muñoz-Hidalgo, Lisandra, San-Miguel, Teresa, Megías, Javier, Monleón, Daniel, Navarro, Lara, Roldán, Pedro, Cerdá-Nicolás, Miguel, López-Ginés, Concha
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864306/
https://ncbi.nlm.nih.gov/pubmed/31751860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.09.001
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