Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer

PURPOSE: Cell-free DNA (cfDNA) offers the potential for minimally invasive genome-wide profiling of tumor alterations without tumor biopsy and may be associated with patient prognosis. Triple-negative breast cancer (TNBC) is characterized by few mutations but extensive somatic copy number alteration...

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Udgivet i:J Clin Oncol
Main Authors: Stover, Daniel G., Parsons, Heather A., Ha, Gavin, Freeman, Samuel S., Barry, William T., Guo, Hao, Choudhury, Atish D., Gydush, Gregory, Reed, Sarah C., Rhoades, Justin, Rotem, Denisse, Hughes, Melissa E., Dillon, Deborah A., Partridge, Ann H., Wagle, Nikhil, Krop, Ian E., Getz, Gad, Golub, Todd R., Love, J. Christopher, Winer, Eric P., Tolaney, Sara M., Lin, Nancy U., Adalsteinsson, Viktor A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2018
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ORIGINAL REPORTS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815405/
https://ncbi.nlm.nih.gov/pubmed/29298117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.76.0033
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