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IFNB/interferon-β regulates autophagy via a MIR1-TBC1D15-RAB7 pathway
Loss of IFNB/interferon-β in mice causes a Parkinson disease-like phenotype where many features, including SNCA/α-synuclein and MAPT/tau accumulation, can be attributed to a late-stage block in autophagic flux. Recently, we identified a mechanism that can explain this phenotype. We found that IFNB i...
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| Pubblicato in: | Autophagy |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7138209/ https://ncbi.nlm.nih.gov/pubmed/31958036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1718384 |
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