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IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative, proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial effects of IFNB1 in experimental breast cancers, clinical translation has been disappointing, possibly due to induction of surv...

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Detalhes bibliográficos
Main Authors: Ambjørn, Malene, Ejlerskov, Patrick, Liu, Yawei, Lees, Michael, Jäättelä, Marja, Issazadeh-Navikas, Shohreh
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590251/
https://ncbi.nlm.nih.gov/pubmed/23221969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22831
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