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IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative, proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial effects of IFNB1 in experimental breast cancers, clinical translation has been disappointing, possibly due to induction of surv...

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Hlavní autoři: Ambjørn, Malene, Ejlerskov, Patrick, Liu, Yawei, Lees, Michael, Jäättelä, Marja, Issazadeh-Navikas, Shohreh
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590251/
https://ncbi.nlm.nih.gov/pubmed/23221969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22831
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