Selective EP2 and Cox-2 inhibition suppresses cell migration by reversing epithelial-to-mesenchymal transition and Cox-2 overexpression and E-cadherin downregulation are implicated in neck metastasis of hypopharyngeal cancer

Cyclooxygenase-2 (Cox-2) has been shown to promote cancer initiation and progression through pleiotropic functions including induction of epithelial-to-mesenchymal transition (EMT) via its predominant product prostaglandin E(2) that binds to the cognate receptor EP2. Hence, pharmacological inhibitio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transl Res
Egile Nagusiak: Watanabe, Yoshihiro, Imanishi, Yorihisa, Ozawa, Hiroyuki, Sakamoto, Koji, Fujii, Ryoichi, Shigetomi, Seiji, Habu, Noboru, Otsuka, Kuninori, Sato, Yoichiro, Sekimizu, Mariko, Ito, Fumihiro, Ikari, Yuichi, Saito, Shin, Kameyama, Kaori, Ogawa, Kaoru
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137058/
https://ncbi.nlm.nih.gov/pubmed/32269737
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak