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Assessment of the Role of C3(H(2)O) in the Alternative Pathway

In this study we investigate the hydrolysis of C3 to C3(H(2)O) and its ability to initiate activation via the alternative pathway (AP) of the complement system. The internal thioester bond within C3 is hydrolyzed by water in plasma because of its inherent lability. This results in the formation of n...

詳細記述

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書誌詳細
出版年:Front Immunol
主要な著者: Fromell, Karin, Adler, Anna, Åman, Amanda, Manivel, Vivek Anand, Huang, Shan, Dührkop, Claudia, Sandholm, Kerstin, Ekdahl, Kristina N., Nilsson, Bo
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136553/
https://ncbi.nlm.nih.gov/pubmed/32296436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00530
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