Obacunone Protects Against Ulcerative Colitis in Mice by Modulating Gut Microbiota, Attenuating TLR4/NF-κB Signaling Cascades, and Improving Disrupted Epithelial Barriers

Obacunone, a natural limonoid compound abundantly distributed in citrus fruits, possesses various biological properties, such as antitumor, antioxidant, and antiviral activities. Recent studies suggested an anti-inflammatory activity of obacunone in vitro, but its efficacy on intestinal inflammation...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Luo, Xiaoping, Yue, Bei, Yu, Zhilun, Ren, Yijing, Zhang, Jing, Ren, Junyu, Wang, Zhengtao, Dou, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136403/
https://ncbi.nlm.nih.gov/pubmed/32296403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00497
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