Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice

Baicalein (5,6,7-trihydroxyflavone), a predominant bioactive component isolated from the root of Scutellaria baicalensis Georgi, has established potent anti-inflammatory activity via multi-targeted mechanisms. However, little is known about the effect of baicalein on 2,4,6-trinitrobenzene sulfonic a...

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Publicat a:Sci Rep
Autors principals: Luo, Xiaoping, Yu, Zhilun, Deng, Chao, Zhang, Jingjing, Ren, Gaiyan, Sun, Aning, Mani, Sridhar, Wang, Zhengtao, Dou, Wei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703971/
https://ncbi.nlm.nih.gov/pubmed/29180692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12562-6
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