Pinocembrin alleviates ulcerative colitis in mice via regulating gut microbiota, suppressing TLR4/MD2/NF-κB pathway and promoting intestinal barrier

Pinocembrin, a plant-derived flavonoid, has a variety of pharmacological activities, including anti-infection, anti-cancer, anti-inflammation, cardiovascular protection, etc. However, the mechanism of pinocembrin on the anti-colitis efficacy remains elusive and needs further investigation. Here, we...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Autores principales: Yue, Bei, Ren, Junyu, Yu, Zhilun, Luo, Xiaoping, Ren, Yijing, Zhang, Jing, Mani, Sridhar, Wang, Zhengtao, Dou, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2020
Materias:
Therapeutics & Molecular Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391130/
https://ncbi.nlm.nih.gov/pubmed/32687156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20200986
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