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Contractile Behavior of Mouse Aorta Depends on SERCA2 Isoform Distribution: Effects of Replacing SERCA2a by SERCA2b

The Sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA) actively pumps Ca(2+) into the sarco/endoplasmic reticulum, thereby regulating intracellular Ca(2+) concentrations and associated physiological processes. Different SERCA isoforms have been described (SERCA1, 2, and 3) with SERCA2 playing a pivo...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Fransen, Paul, Chen, Jialin, Vangheluwe, Peter, Guns, Pieter-Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136392/
https://ncbi.nlm.nih.gov/pubmed/32296344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00282
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