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A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium
The full-length isoform of matrixmetalloproteinase-2 (FL-MMP-2) plays a role in turnover of the cardiac extracellular matrix. FL-MMP-2 is also present intracellularly in association with sarcomeres and, in the setting of oxidative stress, cleaves myofilament proteins with resultant impaired contract...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174733/ https://ncbi.nlm.nih.gov/pubmed/25309453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00363 |
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