N-Terminal Truncated Intracellular Matrix Metalloproteinase-2 Induces Cardiomyocyte Hypertrophy, Inflammation and Systolic Heart Failure

Matrix metalloproteinase-2 (MMP-2) is increasingly recognized as a major contributor to progressive cardiac injury within the setting of ischemia-reperfusion injury and ischemic ventricular remodeling. A common feature of these conditions is an increase in oxidative stress, a process that engages mu...

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Главные авторы: Lovett, David H., Mahimkar, Rajeev, Raffai, Robert L., Cape, Leslie, Zhu, Bo-Qing, Jin, Zhu-Qiu, Baker, Anthony J., Karliner, Joel S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712965/
https://ncbi.nlm.nih.gov/pubmed/23874529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068154
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