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Stochastic Modeling of Autoregulatory Genetic Feedback Loops: A Review and Comparative Study

Autoregulatory feedback loops are one of the most common network motifs. A wide variety of stochastic models have been constructed to understand how the fluctuations in protein numbers in these loops are influenced by the kinetic parameters of the main biochemical steps. These models differ accordin...

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Veröffentlicht in:Biophys J
Hauptverfasser: Holehouse, James, Cao, Zhixing, Grima, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136347/
https://ncbi.nlm.nih.gov/pubmed/32155410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.016
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