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Revisiting the Reduction of Stochastic Models of Genetic Feedback Loops with Fast Promoter Switching

Propensity functions of the Hill type are commonly used to model transcriptional regulation in stochastic models of gene expression. This leads to an effective reduced master equation for the mRNA and protein dynamics only. Based on deterministic considerations, it is often stated or tacitly assumed...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Holehouse, James, Grima, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818172/
https://ncbi.nlm.nih.gov/pubmed/31540707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.021
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