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The stochastic behavior of a molecular switching circuit with feedback

BACKGROUND: Using a statistical physics approach, we study the stochastic switching behavior of a model circuit of multisite phosphorylation and dephosphorylation with feedback. The circuit consists of a kinase and phosphatase acting on multiple sites of a substrate that, contingent on its modificat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krishnamurthy, Supriya, Smith, Eric, Krakauer, David, Fontana, Walter
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904185/
https://ncbi.nlm.nih.gov/pubmed/17540019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-2-13
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