Adaptation by stochastic switching of a monostable genetic circuit in Escherichia coli

Stochastic switching is considered as a cost-saving strategy for adaptation to environmental challenges. We show here that stochastic switching of a monostable circuit can mediate the adaptation of the engineered OSU12-hisC Escherichia coli strain to histidine starvation. In this strain, the hisC ge...

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Bibliografiset tiedot
Päätekijät: Tsuru, Saburo, Yasuda, Nao, Murakami, Yoshie, Ushioda, Junya, Kashiwagi, Akiko, Suzuki, Shingo, Mori, Kotaro, Ying, Bei-Wen, Yomo, Tetsuya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130557/
https://ncbi.nlm.nih.gov/pubmed/21613982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.24
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