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Revisiting the Reduction of Stochastic Models of Genetic Feedback Loops with Fast Promoter Switching

Propensity functions of the Hill type are commonly used to model transcriptional regulation in stochastic models of gene expression. This leads to an effective reduced master equation for the mRNA and protein dynamics only. Based on deterministic considerations, it is often stated or tacitly assumed...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Holehouse, James, Grima, Ramon
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818172/
https://ncbi.nlm.nih.gov/pubmed/31540707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.021
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