Chargement en cours...

mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway

T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy that is characterized by a high frequency of induction failure and by early relapse. Many studies have revealed that metadherin (MTDH) is highly expressed in a variety of malignant solid tumours and plays an impo...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Li, Yiqing, Chen, Jiaoting, Yang, Wenjuan, Liu, Hongyun, Wang, Jieyu, Xiao, Jie, Xie, Shuangfeng, Ma, Liping, Nie, Danian
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136213/
https://ncbi.nlm.nih.gov/pubmed/32251289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2380-9
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!