mPGES-1-Mediated Production of PGE(2) and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation

PGE(2) is a lipid mediator of the initiation and resolution phases of inflammation, as well as a regulator of immune system responses to inflammatory events. PGE(2) is produced and sensed by T cells, and autocrine or paracrine PGE(2) can affect T cell phenotype and function. In this study, we use a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Maseda, Damian, Banerjee, Amrita, Johnson, Elizabeth M., Washington, Mary Kay, Kim, Hyeyon, Lau, Ken S., Crofford, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302013/
https://ncbi.nlm.nih.gov/pubmed/30619314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02954
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